Approximately 17.7 million people died of CVD in 2015 representing 31% of all global deaths 1 and costing about $316.1 billion/year 2. Our findings demonstrate that roughly half of the relationship between NLR and CVEs may be mediated through DM, HT and Cr.Ĭardiovascular diseases (CVDs) are the leading cause of mortality worldwide 1. The total effect of NLR on CVEs was explained partly (44%) by a direct effect and partly (56%) by an indirect effect through DM, HT and Cr. Prevalence rates of HT, DM, and chronic kidney disease were 45.1%, 23.6%, and 16.5%, respectively. The incidence rate of CVE was 8.8/1000/year. A generalized structural equation model and 1,000-replication bootstrapping were applied. Two causal pathways A: NLR→(DM→Cr→HT)→CVEs and B: NLR→(DM → HT→Cr)→CVEs were constructed. The study used data on 2,501 subjects from the Electricity Generating Authority of Thailand cohort 2002–2012. We aimed to explore the extent to which NLR is directly associated with CVEs or mediated through diabetes mellitus (DM), hypertension (HT) and creatinine (Cr). Each issue averages 284 pages in length.Neutrophil to lymphocyte ratio (NLR), an inflammatory biomarker, is associated with cardiovascular events (CVEs), but its causal pathway is unknown. JMF is issued quarterly, in February, May, August, and November Integrative reviews as well as reports on methodological and statistical
Original theory and research using the variety of methods reflective of theįull range of social sciences, including quantitative, qualitative, and multimethodĭesigns. Well as interdisciplinary fields such as human development and family sciences. The Journal also publishes book reviews.Ĭontributors to JMF come from a diversity of fields includingĪnthropology, demography, economics, history, psychology, and sociology, as Original research and theory, research interpretation and reviews, and criticalĭiscussion concerning all aspects of marriage, other forms of close relationships,Īnd families. In the family field and has been so for over sixty years. The Journal of Marriage and Family (JMF), publishedīy the National Council on Family Relations, is the leading research journal Throughout, the author highlights the potential for researchers to elevate measurement to a level on par with theorizing and testing about relationships among constructs. Three basic models are considered: (a) the Rasch and (b) two-parameter logistic models for dichotomous items and (c) the Rating Scale Model for multicategory items. It also offers a didactic example of how the approach can be used to refine conceptualization and operationalization of constructs in the family sciences, using data from the National Longitudinal Survey of Youth 1979 (n = 2,732). The article offers a nontechnical introduction to some key features of IRT, including its orientation toward locating items along an underlying dimension and toward estimating precision of measurement for persons with different levels of that same construct. This article provides family scientists with an understanding of contemporary measurement perspectives and the ways in which item response theory (IRT) can be used to develop measures with desired evidence of precision and validity for research uses.